Tanaka, T; Sewell, H; Waters, S; Phillips, S.E.V; Rabbitts, T.H. (2011) Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LM02 protein interactions using a single VH domain. J. Biol Chem 286: 3707-3716
McCormack, M.P; Young, L.F; Vasudevan, S; de Graaf, C.A; Codrington, R; Rabbitts, T.H; Jane, S.M; Curtis, D.J. (2010) The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal. Science, 327: 879-83
McCaughan, F; Pole, J.C.M; Bankier, A.T; Konfortov, B.A; Carroll, B; Falzon, M; Rabbitts, T.H; George, P.J; Dear, P.H; Rabbitts, P.H. (2010) Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer. Am J Respir Crit Care Med, 182: 83-91
Perez-Martinez, D; Tanaka, T; Rabbitts, T.H. (2010) Intracellular antibodies and cancer: new technologies offer therapeutic opportunities. Bioessays 32: 589-598
Tanaka, T; Rabbitts T.H. (2010) Protocol for the selection of single-domain antibody fragments by third generation intracellular antibody capture. Nature Protocols 2: 67-92
Tanaka, T; Rabbitts, T.H. (2010) Interfering with RAS-effector protein interactions prevent RAS-dependent tumour initiation and causes stop-start control of cancer growth. Oncogene 1-7
Davis, J.J; Tkac, J; Humphreys, R; Buxton, A.T; Lee, T.A; Ko Ferrigno, P. (2009) Peptide aptamers in label-free protein detection II: Chemical optimisation and detection of distinct protein isoforms. Analytical Chemistry May 1;81(9): 3314-20
Rabbitts, T.H.( 2009) Commonality but diversity in cancer gene fusions. Cell 137:391-395
Appert, A; Nam, C-H; Lobato, N; Priego, E; Miguel, R.N; Blundell, T; Drynan, L; Sewell, H; Tanaka, T; Rabbitts, T.H. (2009) Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia Cancer Res, 69: 4784-4790
Blakaj, D.M; Fernandez-Fuentes, N; Chen, Z; Hegde, R; Fiser, A; Burk, R.D; Brenowitz, M. 2009 Evolutionary and biophysical relationships among the papillomavirus E2 proteins. Frontiers in Bioscience 14:900-917
Tanaka, T; Rabbitts, T.H. 2009 Selection of complementary single-variable domains for building monoclonal antibodies to native proteins. Nucleic Acids Res 1-8 doi: 10.1093/nar/gkp069
Andrews, W; Barber, M; Hernadez-Miranda, L.R; Xian, J; Rakic, S; Sundaresan, V; Rabbitts, T.H; Pannell, R; Rabbitts, P.H; Thompson, H; Erskine, L; Murakami, F; Parnavelas, J.G. 2008 The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons Dev Bio 313: 648-658
Cano, F; Pannel, R; Follows, G.A; Rabbitts, T.H. 2008 Preclinical modelling of cytosine arabinoside response in Mll-Enl translocator leukemias Mol Cancer Ther 7: 730-735
Cano, F; Drynan, L.F; Pannel, R; Rabbitts, T.H. 2008 Leukaemia lineage specification caused by cell-specific Mll-Enl translocations Oncogene 27: 1945-1950
Evans, D; Johnson, S; Laurenson, S; Davies, A.G; Ko Ferrigno, P; Wälti, C. 2008 Electrical protein detection in cell lysates using high-density peptide-aptamer microarrays. J Biol 7(1):3
Estrela, P; Paul, D; Li, P; Keighley, S.D; Migliorato, P; Laurenson, S; Ko Ferrigno, P. 2008 Label-free detection of protein interactions with peptide aptamers by open circuit potential measurement. Acta Electrochimica 53(22):6489-6496
Ibbotson, R.H; Dunn, R.J; Djakov, V; Ko Ferrigno, P; Huq, S.E. Polyimide microcantilever surface stress sensor using low-cost, rapidly-interchangeable, spring-loaded microprobe connections. Microelectronic Engineering Article in Press, doi:10.1016/j.mee.2007.12.065
Johnson, S; Evans, D; Laurenson, S; Paul, D; Davies, A.G; Ko Ferrigno, P; Wälti, C. 2008 Surface-immobilized peptide aptamers as probe molecules for protein detection. Anal Chem Feb 15;80(4):978-83
Kukol, A; Li, P; Estrela, P; Ko-Ferrigno, P; Migliorato, P. 2008 Label-free electrical detection of DNA hybridization for the example of influenza virus gene sequences. Anal Biochem Mar 1;374(1):143-53
Nam, C-H; Lobato, M.N; Appert, A; Drynan, L.F; Rabbitts, T.H. 2008 An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions Oncogene, e1-7
Rodriguez-Perales, S; Cano, F; Lobato, M.N; Rabbitts, T.H. 2008 MLL gene fusions in human leukaemias: in vivo modelling to recapitulate these primary tumourigenic events Int J Hematol 87: 3-9
Shu, W; Laurenson, S; Ko Ferrigno, P; Seshia, A.A. 2008 Label free protein fishing from cell lysates. Biosensors and Bioelectronics, 24:233-237
Tanaka, T; Rabbitts, T.H. 2008 Functional intracellular antibody fragments do not require invariant intra-domain disulfide bonds J Mol Biol 376: 749-757
Tanaka, T; Rabbitts, T.H 2008 Interfering with protein-protein interactions: potential for cancer therapy Cell Cycle 7: 1569-1574
Aitchison, A; Warren, A; Neal, D; Rabbitts, P. 2007 RASSF1A promoter methylation is frequently detected in both pre-malignant and non-malignant microdissected prostatic epithelial tissues Prostate 67:638-644
Davis, J.J; Tkac, J; Laurenson, S; Ko Ferrigno, P. 2007 Peptide aptamers in label-free protein detection: 1. Characterization of the immobilized scaffold Anal Chem 79:1089-1096
Fernandez-Fuentes, N; Rai, B.K; Madrid-Aliste, C.J; Fajardo, J.E; Fiser, A. 2007 Comparative protein structure modeling by combining multiple templates and optimizing sequence-to-structure alignments. Bioinformatics 23:2558-65
Fernandez-Fuentes, N; Madrid-Aliste, C.J; Rai, B.K; Fajardo, J.E; Fiser, A. 2007 M4T: a comparative protein structure modeling server. Nucleic Acids Res. 35:W363-8
Hermoso, A; Espadaler, J; Querol, E; Aviles, FX; Sternberg, MJE; Oliva, B; Fernandez-Fuentes, N. 2007 ArchDB: Including Functional Annotations and Expanding the Database of Classified Structural Motifs Bioinformatics and Biology Insights 1:77-90
George, P.J; Banerjee A; Read, C.A; OSullivan C; Falzon, M; Pezzella F; Nicholson, A; Shaw P; Laurent, G; Rabbitts, P.H. 2007 Surveillance for the detection of early lung cancer in patients with bronchial dysplasia Thorax 62:43-50
Torres, M; Fernandez-Fuentes, N; Fiser, A; Casadevall, A. 2007 The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen. J Biol Chem 282:13917-27
Tanaka, T; Williams, R; & Rabbitts T.H. 2007 Tumour prevention by a single antibody domain targeting the interaction of signal transduction proteins with RAS EMBO J. 26: 3250-3259
Torres, M; Fernandez-Fuentes, N; Fiser, A; Casadevall, A 2007 Heterologous constant chains impart kinetic and thermodynamic differences in antigen binding for immunoglobulins with identical variable-regions Plos ONE. 12:2
Torres, M; Fernandez-Fuentes, N; Fiser, A; Casadevall, A 2007 The immunoglobulin heavy chain constant region affects kinetic and thermodynamic parameters of antibody variable region interactions with antigen J.B.C. 282: 13917-13927